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Impactful Breast Cancer Publications

Featured impactful basic research, translational research, behavioral science and clinical care research from members of the Ginny L Clements Breast Cancer Institute.

2024

  • Amgad M, Hodge JM, Elsebaie MAT, Bodelon C, Puvanesarajah S, Gutman DA, Siziopikou KP, Goldstein JA, Gaudet MM, Teras LR, Cooper LAD. A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer. doi: 10.1038/s41591-023-02643-7. PMID: 38012314. Nature Medicine, 30:85-97, 2024.
  • Cooper LA and Siziopikou KP: Research Briefing: A population-level computational histologic signature for invasive breast cancer prognosis. Nature Medicine, 30: 41-42, 2024.
  • Quintela-Fandino M, Bermejo B, Zamora E, Moreno F, García-Saenz JÁ, Pernas S, Martínez-Jañez N, Jiménez D, Adrover E, de Andrés R, Mourón S, Bueno MJ, Manso L, Viñas G, Alba E, Llombart-Cussac A, Cortés J, Tebar C, Roe DJ, Grant A, Watson A, Colomer R, Mouneimne G. High Mechanical Conditioning by Tumor Extracellular Matrix Stiffness Is a Predictive Biomarker for Antifibrotic Therapy in HER2-Negative Breast Cancer. doi: 10.1158/1078-0432.CCR-24-1518. PMID: 39283720. Clinical Cancer Research, 30(22):5094-5104, 2024.
  • Kramer JM, Jordan SG, Chiang JA. Use of the lateral arm in tomosynthesis-guided SCOUT Reflector placement procedures. doi: 10.1016/j.clinimag.2024.110130. PMID: 38490080. Clinical Imaging, 109:110130, 2024
  • Li X, Nguyen TTA, Zhang J, Nayak A, Liu Y, Duckworth LA, Zhang G, Bakkar R, Agarwal I, Hou Y, Guo H, Huang X, Wei S, Yasmeen S, Khoury T, Huang H, Zhang H, Smith GH, Turashvili G, Peng L, Liu Y, Yang W, Siziopikou KP. Validation Study of the Newly Proposed Refined Diagnostic Criteria for Malignant Phyllodes Tumor With 136 Borderline and Malignant Phyllodes Tumor Cases. doi: 10.1097/PAS.0000000000002264. PMID: 38934254. The American Journal of Surgical Pathology, 48(9):1146-1153, 2024
  • Cheng JN, Frye JB, Whitman SA, Ehsani S, Ali S, Funk JL. Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice. doi: 10.1210/endocr/bqae038. PMID: 38715255. Endocrinology, 165(6):bqae038, 2024

2025

  • Boyer JA, Sharma M, Dorso MA, Mai N, Amor C, Reiter JM, Kannan R, Gadal S, Xu J, Miele M, Li Z, Chen X, Chang Q, Pareja F, Worland S, Warner D, Sperry S, Chiang GG, Thompson PA, Yang G, Ouerfelli O, de Stanchina E, Wendel HG, Rosen EY, Chandarlapaty S, Rosen N. eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer. doi: 10.1073/pnas.2424286122. PMID: 38766126. Proceedings of the National Academy of Sciences of the United States of America, 122(30):e2424286122, 2025.
  • Hadeed M, Badger TA, Segrin C, Robles-Morales R, Werts-Pelter SJ. Strategies for recruitment and retention of diverse and underserved cancer survivor and caregiver dyads in clinical trials. doi: 10.1016/j.conctc.2024.101425. PMID: 39881887. Contemporary Clinical Trials Communications, 44:101425, 2025.
  • Segrin C, Sikorskii A, Cunicelli N, Badger T. Moderators of interdependent psychological distress in cancer survivor-caregiver dyads. doi: 10.1080/07347332.2025.2450012. Epub 2025 Jan 9. PMID: 39780689. Journal of Psychosocial Oncology, 43(4):574-592, 2025.
  • Rakha EA, Quinn C, Raymond W, Allison KH, Badve SS, Brogi E, Callagy G, Charafe-Jauffret E, Chen CJ, Chen YY, Collins LC, Cserni G, Djerroudi L, Jaffer S, Foschini MP, Gobbi H, Gudi M, Harada O, Kulka J, Kuroda H, Lakhani SR, Li X, Moriya T, O'Toole SA, Pinder SE, Provenzano E, Sahin AA, Schmitt F, Shaaban AM, Siziopikou KP, Tang P, Tse GM, Varga Z, Vincent-Salomon A, Wen H, Yamaguchi R, Yang W, Fox SB, Schnitt SJ, Ellis IO, Tan PH. Classification of Fibroepithelial Lesions of the Breast in Core Needle Biopsy With Implications for Further Management. doi: 10.1016/j.modpat.2025.100734. PMID: 39947480. Modern Pathology, 38(5):100734, 2025.
  • Warner EL, Sikorskii A, Cunicelli N, Badger T, Segrin C, Morrill KE, Rainbow J. Employment Productivity and Cancer-Related Psychological Symptoms Among Adult Cancer Dyads. doi: 10.1097/JOM.0000000000003334. PMID: 39905918. Occupational and Environmental Medicine, 67(5):e294-e301, 2025.
  • Segrin C, Badger TA, Cunicelli N, Sikorskii A. Effects of an Interpersonal Counseling Intervention on Interdependence of Symptoms in Cancer Survivor-Informal Caregiver Dyads. doi: 10.1002/pon.70250. PMID: 40760764. Psycho-Oncology, 34(8):e70250, 2025.
  • Banwait R, Ko H, Michalek J, Liu Q, Lathrop K, Bowhay-Carnes E, Fotopoulos G, Sarantopoulos J, Elledge R, Taverna J, Karnad A, Siziopikou KP, Kaklamani V. Pilot phase II study of the combination of lenvatinib (L) and eribulin (E) in advanced solid tumors. doi: 10.1002/ijc.35446. PMID: 40232157. International Journal of Cancer, 157(4):752-759, 2025.
  • Tan PH, Ellis IO, Allison KH, Badve SS, Brogi E, Callagy G, Charafe-Jauffret E, Chen CJ, Chen YY, Collins LC, Cserni G, Djerroudi L, Foschini MP, Fox SB, Gobbi H, Gudi M, Harada O, Jaffer S, Kulka J, Kuroda H, Lakhani SR, Li X, Moriya T, O'Toole S, Pinder SE, Provenzano E, Quinn C, Raymond W, Sahin AA, Schmitt F, Shaaban AM, Shet T, Siziopikou KP, Tang P, Tse GM, Varga Z, Vincent-Salomon A, Wen H, Yamaguchi R, Yang W, Schnitt SJ, Rakha EA. Malignant phyllodes tumours of the breast: the case for revising WHO's 'full house' diagnostic criteria. doi: 10.1111/his.15455. PMID: 40223225; Histopathology, 87(2):169-182, 2025.
  • Anh Nguyen TT, Zhang J, Iqbal J, Ahmed SS, Liu Y, Yang L, Zhang G, Ning B, Guo H, Wei S, Hou Y, Agarwal I, Yasmeen S, Khoury T, Ai D, Deng H, Liu Y, Peng L, Chen YY, Siziopikou KP, Li X. Proposing New Criteria for Classification of Benign Fibroepithelial Lesions Based on Clinicopathologic Evaluations of 507 Cases with Clinical Outcome. doi: 10.1016/j.modpat.2025.100812. PMID: 40516609. Modern Pathology, 38(10):100812, 2025.
  • Schuster E, Dashzeveg NK, Tong F, Jia Y, El-Shennawy L, Zhang T, Hoffman AD, Kitata RB, Kibria G, Zhang Y, Squires JR, Zheng C, Ramos E, Taftaf R, Scholten D, Almubarak HF, Adorno-Cruz V, Sullivan DP, Reduzzi C, Minor AC, Purev-Ochir W, Spahija S, Xu R, Siziopikou KP, Platanias LC, Shah A, Muller WA, Gradishar WJ, Cristofanilli M, Tsai CF, Shi T, Liu H. Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis. doi: 10.1038/s41467-025-62862-z. PMID: 40818975. Nature Communications, 16(1):7649, 2025.
  • Hagio T, Galons JP, Roe D, Marron MT, Thomson C, Thompson P, Stopeck AT, Bilgin A, Altbach MI, Chiang JA. Concurrent water T2 and fat fraction mapping of the breast using the radial gradient and spin echo (RADGRASE) pulse sequence. doi: 10.1016/j.mri.2025.110355. PMID: 39921152. Magnetic Resonance Imaging, 118:110355, 2025.
  • Larsen T, Tseng HW, Chiang JA, Vedantham S. Soft-tissue lesion and microcalcification detectability in cone-beam breast CT: cascaded system analysis. doi: 10.1117/1.JMI.12.6.063501. PMID: 41404593. Journal of Medical Imaging (Bellingham), 12(6):063501, 2025.
  • Tseng HW, Fu Z, Vedantham S. Simultaneous reduction of radiation dose and scatter-to-primary ratio using a truncated detector and advanced algorithms for dedicated cone-beam breast CT. doi: 10.1088/2057-1976/adb8f1. PMID: 39983239. Biomedical Physics & Engineering Express, 11(2):025047, 2025.
  • Escoto A, Hecksel R, Parkinson C, Crane S, Atwell B, King S, Ortiz Chavez D, Jannuzi A, Sands B, Bitler BG, Fehniger TA, Paek AL, Padi M, Schroeder J. Nuclear EGFR in breast cancer suppresses NK cell recruitment and cytotoxicity. doi: 10.1038/s41388-024-03211-0. PMID: 39521886. Oncogene, 44(5):288-295, 2025.
  • Wright LE, Frye JB, Kunihiro AG, Timmermann BN, Funk JL. Comparative Effects of Turmeric Secondary Metabolites Across Resorptive Bone Diseases. doi: 10.3390/metabo15040266. PMID: 40278395. Metabolites, 15(4):266, 2025.
  • Yue Y, Lima SM, Hovey KM, Bea JW, Wactawski-Wende J, Manson JE, Roe D, Funk JL, Odegaard AO, Ziller SG, Wallace R, Jung SY, Cauley JA, Ochs-Balcom HM. Follicle stimulating hormone, luteinizing hormone and adiposity trajectories in postmenopausal women. doi: 10.1080/13697137.2025.2595986. PMID: 41428435. Climacteric, 29(3):409-415, 2026.
  • Larkey LK, James DL, Han S, Weihs K, Jahnke R, Oh B, Kim SW, Huberty J, Petrov ME, Martin D, Howe N, Hook J, Soltero E, Rao S, Northfelt D. Randomized controlled trial testing Tai Chi Easy/Qigong and Sham Qigong on breast cancer survivors' fatigue and associated symptoms. doi: 10.1016/j.ctcp.2025.102014. PMID: 40651067. Complementary Therapies in Clinical Practice, 61:102014, 2025.
  • Wallace R, Smith I, Day D, Alexander M, Weihs KL, Wiley JF. A randomized controlled trial: Evaluating whether a cognitive behavioral internet-delivered intervention targeting emotion regulation improves health-related quality of life in cancer survivors. doi: 10.1037/hea0001497. PMID: 40208747. Health Psychology, 44(10):909-921, 2025.
  • Harel K, Czamanski-Cohen J, Cohen M, Lane RD, Dines M, Caspi O, Weihs KL. Differences in Emotional Awareness Moderate Cytokine-Symptom Associations Among Breast Cancer Survivors. doi: 10.1016/j.bbi.2024.12.005. PMID: 39674559. Brain, Behavior, and Immunity, 124:387-396, 2025.
  • Goldman CM, Chuning AE, Lane RD, Smith R, Weihs KL. Emotional awareness amplifies affective sensitivity to social support for women with breast cancer. doi: 10.1177/13591053241291018. PMID: 39449575. Journal of Health Psychology, 30(13):3803-3819, 2025.
  • Mouneimne G, Connors C, Watson A, Grant A, Campo D, Ring A, Kaur P, Lang JE. Mechanical Conditioning (MeCo) Score Progressively Increases Through the Metastatic Cascade in Breast Cancer via Circulating Tumor Cells. doi: 10.3390/cancers17101632. PMID: 40427129. Cancers (Basel), 17(10):1632, 2025.

2026

  • Maynard L, Donohue C, Cook A, Ehsani S, Neumayer L, Foster N. Collaborative model between breast surgery and genetic counseling reduces wait times and increases pretesting genetic counseling volume. doi: 10.1016/j.surg.2026.110085. PMID: 41759262. Surgery, 193:110085, 2026.
  • Ruiz-Sepulveda JL, Bueno MJ, Mouron S, Jimenez-Renard V, Muñoz M, Moradiellos M, Garma LD, García-Jimeno L, Watson AW, Mouneimne G, Park S, Jimeno R, Quintela-Fandino M. Osteopontin mediates acquired resistance to hypoxia-inducing antiangiogenics and promotes anti-PD-L1 refractoriness in breast cancer models. doi: 10.1172/JCI174092. PMID: 42454487. Journal of Clinical Investigation, 136(14):e174092, 2026.
  • Segrin C, Badger TA, Morrill KE, Sikorskii A. Neighborhood disadvantage and social isolation are associated with psychological and physical symptom burden in cancer survivors. doi: 10.1080/13548506.2025.2564313. PMID: 41017638. Psychology, Health & Medicine, 31(7):1678-1692, 2026.
  • Chriswell A, Skiba MB, Badger TA, Recio-Boiles A, Fox RS. Applying Innovative Methods to Develop Health Education Text Messages in Cancer Survivorship. doi: 10.1007/s13187-025-02826-5. PMID: 41524846. Journal of Cancer Education, 2026.
  • Skiba MB, Nelson MA, Badger TA, Chriswell A, Recio-Boiles A, Segrin C, Fox RS. Applying Virtual Community Engagement Studio to Inform a Dyadic Text Message Intervention for Diet, Physical Activity, and Sleep After Cancer. doi: 10.1177/10732748261424956. PMID: 41650165. Cancer Control, 33:10732748261424956, 2026.
  • McDougall R, Shi Y, Robbins J, Hsu C, Wang L. COVID-19 as a Catalyst for Ultra-Hypofractionated Radiotherapy in Early Breast Cancer: Trends, Predictors, and Estimated Cost Savings. doi: 10.1016/j.clbc.2026.06.004. PMID: 42413343. Clinical Breast Cancer, 26(8):1-6, 2026.
  • Larsen TC, Tseng HW, Ross W, Araujo S, Wu P, Haneda E, Davis C, Karellas A, Vedantham S. Development and performance evaluation of an upright dedicated cone-beam breast CT system. doi: 10.1002/mp.70664. PMID: 42682195. Medical Physics, 53(9):e70664, 2026.
  • Hadeed MC, Segrin C, Sikorskii A, Garcia DO, Bea J, Badger TA. Baseline self-efficacy and engagement in a symptom management intervention after cancer treatment: an exploratory analysis of a sequential multiple assignment randomized trial. doi: 10.1007/s11764-026-02040-2. PMID: 42141337. Journal of Cancer Survivorship, 2026.
  • Park S, Badger TA, Segrin C, Skiba MB, Guest DD, Sussman A. Longitudinal associations among loneliness and physical and psychological well-being in older cancer survivors. doi: 10.1007/s11764-026-02052-y. PMID: 42228050 Journal of Cancer Survivorship, 2026.
  • Lima SM, Yue Y, Bea JW, Hovey KM, Wactawski-Wende J, Manson JE, Roe DJ, Funk JL, Odegaard A, Ziller SG, Allison M, Wallace R, Jung SY, Cauley JA, Ochs Balcom HM. Gonadotropin trajectories among postmenopausal women not using hormone therapy. doi: 10.1097/GME.0000000000002631. PMID: 40891652. Menopause, 33(1):3-11, 2026.
  • Nicholas T, Hamann HA, Price SN, Weihs K. Coping strategies and changes in depressive symptoms: Insights from a collaborative care intervention for individuals facing cancer in underserved communities. doi: 10.1080/07347332.2025.2542451. PMID: 40791161. Journal of Psychosocial Oncology, 44(2):174-187, 2026.
  • Mitchel OR, Hsu CP, Millheiser LS, Wapnir IL, Chandak S, Tran M, Erdrich J. Survival Outcomes in Breast Cancer Patients With Use of Vaginal Estrogen Therapy: A SEER Analysis. doi: 10.1200/OP-26-00972. PMID: 42361283;. Erratum in: JCO Oncology Practice, OP2600972/OP2501142, 2026.
  • Erdrich J, Woriax HE, Thomas A, Huyser MR. Hidden in the Data: Breast Cancer Patterns, Gaps, and Challenges for Native American Women. doi: 10.1007/s12609-025-00629-7. PMID: 41510308. Current Breast Cancer Reports, 18(1):4, 2026.
  • Haw Y, Krings G, Hsiao WY, Zhan H, Hou Y, Zhang G, Zhang H, Wei S, Yang W, Laé M, Post MD, Liu Y, Shamir ER, Rosa M, Siziopikou KP, Schnitt S, Chen YY, Li X. Clinicopathologic Analyses of 34 Cases of High-Grade Serous-Like Carcinoma (HG-SL-Ca) of the Breast. doi: 10.1097/PAS.0000000000002516. PMID: 41735183. American Journal of Surgical Pathology, 50(5):543-549, 2026.