Phase 1

The phase I program at the University of Arizona Cancer Center conducts cutting-edge early clinical trials across a broad spectrum of solid and hematologic cancers for patients whose cancer progressed on standard chemotherapy. Our phase I team provide patients with a comprehensive and unique care approach focused on cancer treatment, nutrition, optimal physical activity, and mental health wellbeing through diverse specialists and support groups at our cancer center. Our team is comprised of outstanding oncologists/investigators, investigational pharmacists, nurse practitioners, research nurses, and research coordinators with several years of experience whose main focus is patient care and providing best therapeutic options through discovery.

The Early Phase clinical trials team goals:

  • Provide patients with world-class compassionate care through a dedicated multidisciplinary team approach.
  • Conduct innovative cutting-edge early clinical trials across a broad spectrum of hematologic and solid cancers.
  • Conduct comprehensive genetic testing through expanded molecular profiling to identify targetable mutations for cancers.
  • Our phase I lab scientist strive to develop new drugs to fight cancer and identify new biomarkers to assess response to treatment.
  • Access to a genetic counselor to test for hereditary diseases.
  • To educate the next generation of investigators and oncologists.

Featured Clinical Trials

An Open-Label, Multicenter, Dose Escalation, Phase IA/IB Study to Evaluate Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281, an Immunocytokine Consisting of Interleukin 2 Variant (IL-2v) Targeting Fibroblast Activation Protein-Alpha (FAP), as a Single Agent (Part A) or in Combination with Trastuzumab or Cetuximab (Part B or C)

A Phase 1 Dose Escalation Study Evaluating the Safety and Tolerability of PF-06804103 in Patients with Human Epidermal Growth Factor Receptor 2 (HER2) Positive Solid Tumors


Medical Oncology


Medical Oncology
Gynecologic Oncology
Medical Oncology



Clinical Research Nursing

Diane Rensvold, RN
Lynnette Theiss, Senior Research RN

Clinical Research Coordination

Ivette Arias
Jose Armando Bermudez Rodriguez

Research Data Coordination

Janet Huynh, BA
Samuel S Kraus, BHS

Regulatory Coordination

Sarah Martinez, MPH
(520) 626-9756

Admin Support

Lora Macias

Program Manager

Ruth Cañamar, BA