2020
Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry.
Zhang G, Keener JE, Marty MT. 2020. Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry. Anal Chem. 92:5666–5669. doi:10.1021/acs.analchem.0c00786.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Sinha SC, Emmadi R, Hoskins K, Danciu O, et al. 2020. Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity. Proc Natl Acad Sci U S A. 117:7961–7970. doi:10.1073/pnas.1921325117.
Molecular and phenotypic characterization of an early T-cell precursor acute lymphoblastic lymphoma harboring PICALM-MLLT10 fusion with aberrant expression of B-cell antigens.
Khurana S, Melody ME, Ketterling RP, Peterson JF, Luoma IM, Vazmatzis G, Tun HW, Foran JM, Jiang L. 2020. Molecular and phenotypic characterization of an early T-cell precursor acute lymphoblastic lymphoma harboring PICALM-MLLT10 fusion with aberrant expression of B-cell antigens. Cancer Genet. 240:40–44. doi:10.1016/j.cancergen.2019.11.002.
Monasone Naphthoquinone Biosynthesis and Resistance in Fungi.
Li M, Kang L, Ding X, Liu J, Liu Q, Shao Y, Molnár I, Chen F. 2020. Monasone Naphthoquinone Biosynthesis and Resistance in Fungi. mBio. 11. doi:10.1128/mBio.02676-19.
Multifaceted roles of TAK1 signaling in cancer.
Mukhopadhyay H, Lee NY. 2020. Multifaceted roles of TAK1 signaling in cancer. Oncogene. 39:1402–1413. doi:10.1038/s41388-019-1088-8.
Nonimmunoglobulin Crystal-Storing Histiocytosis (CSH): Case Report and Literature Review.
Beltran M, Khurana S, Gil Y, Lewis JT, Kumar R, Foran JM. 2020. Nonimmunoglobulin Crystal-Storing Histiocytosis (CSH): Case Report and Literature Review. Case Rep Hematol. 2020:8856411. doi:10.1155/2020/8856411.
Notch3 promotes prostate cancer-induced bone lesion development via MMP-3.
Ganguly SS, Hostetter G, Tang L, Frank SB, Saboda K, Mehra R, Wang L, Li X, Keller ET, Miranti CK. 2020. Notch3 promotes prostate cancer-induced bone lesion development via MMP-3. Oncogene. 39:204–218. doi:10.1038/s41388-019-0977-1.
Novel insights into filament-forming enzymes.
Park CK, Horton NC. 2020. Novel insights into filament-forming enzymes. Nat Rev Mol Cell Biol. 21:1–2. doi:10.1038/s41580-019-0188-1.
Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
Li Y, Zhao J, Gutgesell LM, Shen Z, Ratia K, Dye K, Dubrovskyi O, Zhao H, Huang F, Tonetti DA, et al. 2020. Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J Med Chem. 63:7186–7210. doi:10.1021/acs.jmedchem.0c00456.
Nucleoside Reverse Transcriptase Inhibitor Interaction with Human Equilibrative Nucleoside Transporters 1 and 2.
Miller SR, Hau RK, Jilek JL, Morales MN, Wright SH, Cherrington NJ. 2020. Nucleoside Reverse Transcriptase Inhibitor Interaction with Human Equilibrative Nucleoside Transporters 1 and 2. Drug Metab Dispos. 48:603–612. doi:10.1124/dmd.120.090720.
Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity.
Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, et al. 2020. Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity. Immunity. 53:925–933.e4. doi:10.1016/j.immuni.2020.10.004.
Overexpression of MYB in the Skin Induces Alopecia and Epidermal Hyperplasia.
Hu Y, Song Z, Chen J, Caulin C. 2020. Overexpression of MYB in the Skin Induces Alopecia and Epidermal Hyperplasia. J Invest Dermatol. 140:1204–1213.e5. doi:10.1016/j.jid.2019.10.013.
Pancreatic cancer.
Mizrahi JD, Surana R, Valle JW, Shroff RT. 2020. Pancreatic cancer. Lancet. 395:2008–2020. doi:10.1016/S0140-6736(20)30974-0.
Phosphoprotein-based Biomarkers as a Prognostic for Cancer Therapy, PNAS 117 (31) 18401-18411.
Carter A, Tan C, Pozo K, Telange K, Molinaro R, Guo A, De Rosa E, Martinez J, Zhang S, Takahashi M, et al. 2020. Phosphoprotein-based Biomarkers as a Prognostic for Cancer Therapy, PNAS 117 (31) 18401-18411.
PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer.
Chauhan SS, Toth RK, Jensen CC, Casillas AL, Kashatus DF, Warfel NA. 2020. PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer. Oncogene. 39:2597–2611. doi:10.1038/s41388-020-1168-9.
Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness.
Carcamo-Orive I, Henrion MYR, Zhu K, Beckmann ND, Cundiff P, Moein S, Zhang Z, Alamprese M, D’Souza SL, Wabitsch M, et al. 2020. Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness. PLoS Comput Biol. 16:e1008491. doi:10.1371/journal.pcbi.1008491.
Progress in determining response to treatment in gastrointestinal stromal tumor.
Arshad J, Ahmed J, Subhawong T, Trent JC. 2020. Progress in determining response to treatment in gastrointestinal stromal tumor. Expert Rev Anticancer Ther. 20:279–288. doi:10.1080/14737140.2020.1745068.
Proximal Tubular Vacuolization and Hypersensitivity to Drug-Induced Nephrotoxicity in Male Mice With Decreased Expression of the NADPH-Cytochrome P450 Reductase.
Ding L, Li L, Liu S, Bao X, Dickman KG, Sell SS, Mei C, Zhang Q-Y, Gu J, Ding X. 2020. Proximal Tubular Vacuolization and Hypersensitivity to Drug-Induced Nephrotoxicity in Male Mice With Decreased Expression of the NADPH-Cytochrome P450 Reductase. Toxicol Sci. 173:362–372. doi:10.1093/toxsci/kfz225.
Randomized controlled trial of supportive care interventions to manage psychological distress and symptoms in Latinas with breast cancer and their informal caregivers.
Badger TA, Segrin C, Sikorskii A, Pasvogel A, Weihs K, López AM, Chalasani P. 2020. Randomized controlled trial of supportive care interventions to manage psychological distress and symptoms in Latinas with breast cancer and their informal caregivers. Psychol Health. 35:87–106. doi:10.1080/08870446.2019.1626395.
Role of oxygen in fetoplacental endothelial responses: hypoxia, physiological normoxia, or hyperoxia?
Zhou C, Zou Q-Y, Jiang Y-Z, Zheng J. 2020. Role of oxygen in fetoplacental endothelial responses: hypoxia, physiological normoxia, or hyperoxia?. Am J Physiol Cell Physiol. 318:C943-C953. doi:10.1152/ajpcell.00528.2019.
RPS28B mRNA acts as a scaffold promoting cis-translational interaction of proteins driving P-body assembly.
Fernandes N, Buchan JR. 2020. RPS28B mRNA acts as a scaffold promoting cis-translational interaction of proteins driving P-body assembly. Nucleic Acids Res. 48:6265–6279. doi:10.1093/nar/gkaa352.
Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex.
Navratilova E, Nation K, Remeniuk B, Neugebauer V, Bannister K, Dickenson AH, Porreca F. 2020. Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex. Pain. 161:609–618. doi:10.1097/j.pain.0000000000001748.
Skeletal impact of 17β-estradiol in T cell-deficient mice: age-dependent bone effects and osteosarcoma formation.
Cheng JN, Frye JB, Whitman SA, Funk JL. 2020. Skeletal impact of 17β-estradiol in T cell-deficient mice: age-dependent bone effects and osteosarcoma formation. Clin Exp Metastasis. 37:269–281. doi:10.1007/s10585-019-10012-3.
Smartphone epifluorescence microscopy for cellular imaging of fresh tissue in low-resource settings.
Zhu W, Pirovano G, O’Neal PK, Gong C, Kulkarni N, Nguyen CD, Brand C, Reiner T, Kang D. 2020. Smartphone epifluorescence microscopy for cellular imaging of fresh tissue in low-resource settings. Biomed Opt Express. 11:89–98. doi:10.1364/BOE.11.000089.
Survival following allogeneic transplant in patients with myelofibrosis.
Gowin K, Ballen K, Ahn KW, Hu Z-H, Ali H, Arcasoy MO, Devlin R, Coakley M, Gerds AT, Green M, et al. 2020. Survival following allogeneic transplant in patients with myelofibrosis. Blood Adv. 4:1965–1973. doi:10.1182/bloodadvances.2019001084.
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