2019
Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell-Cell Biophysical Properties in Prostate Cancer.
Rubenstein CS, Gard JMC, Wang M, McGrath JE, Ingabire N, Hinton JP, Marr KD, Simpson SJ, Nagle RB, Miranti CK, et al. 2019. Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell-Cell Biophysical Properties in Prostate Cancer. Cancer Res. 79:4703–4714. doi:10.1158/0008-5472.CAN-19-0868.
Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch.
Fujimaki K, Li R, Chen H, Della Croce K, Zhang HH, Xing J, Bai F, Yao G. 2019. Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch. Proc Natl Acad Sci U S A. 116:22624–22634. doi:10.1073/pnas.1915905116.
Guidelines of care for the management of primary cutaneous melanoma.
Swetter SM, Tsao H, Bichakjian CK, Curiel-Lewandrowski C, Elder DE, Gershenwald JE, Guild V, Grant-Kels JM, Halpern AC, Johnson TM, et al. 2019. Guidelines of care for the management of primary cutaneous melanoma. J Am Acad Dermatol. 80:208–250. doi:10.1016/j.jaad.2018.08.055.
Hendricks WPD, Briones N, Halperin RE, Facista S, Heaton PR, Mahadevan D, and Kim S. (2019) PD-1-associated gene expression signature of neoadjuvant trastuzumab-treated tumors correlates with patient survival in HER2-positive breast cancer Cancers
Hendricks WPD, Briones N, Halperin RE, Facista S, Heaton PR, Mahadevan D, and Kim S. (2019) PD-1-associated gene expression signature of neoadjuvant trastuzumab-treated tumors correlates with patient survival in HER2-positive breast cancer Cancers. 2019.
Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency.
Buehler J, Carpenter E, Zeltzer S, Igarashi S, Rak M, Mikell I, Nelson JA, Goodrum F. 2019. Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency. PLoS Pathog. 15:e1008037. doi:10.1371/journal.ppat.1008037.
Human ALKBH3-induced mA demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells.
Woo H-H, Chambers SK. 2019. Human ALKBH3-induced mA demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells. Biochim Biophys Acta Gene Regul Mech. 1862:35–46. doi:10.1016/j.bbagrm.2018.10.008.
Human Cytomegalovirus pUL37x1 Is Important for Remodeling of Host Lipid Metabolism.
Xi Y, Harwood S, Wise LM, Purdy JG. 2019. Human Cytomegalovirus pUL37x1 Is Important for Remodeling of Host Lipid Metabolism. J Virol. 93. doi:10.1128/JVI.00843-19.
Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC.
Toth RK, Tran JD, Muldong MT, Nollet EA, Schulz VV, Jensen CC, Hazlehurst LA, Corey E, Durden D, Jamieson C, et al. 2019. Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC. Am J Clin Exp Urol. 7:297–312.
Identification of a noncanonical RNA binding domain in the U2 snRNP protein SF3A1.
Martelly W, Fellows B, Senior K, Marlowe T, Sharma S. 2019. Identification of a noncanonical RNA binding domain in the U2 snRNP protein SF3A1. RNA. 25:1509–1521. doi:10.1261/rna.072256.119.
Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research.
Pellizzari ED, Woodruff TJ, Boyles RR, Kannan K, Beamer PI, Buckley JP, Wang A, Zhu Y, Bennett DH. 2019. Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. Environ Health Perspect. 127:126001. doi:10.1289/EHP5133.
Impact of ruxolitinib on myelofibrosis patients post allogeneic stem cell transplant-a pilot study.
Pu JJ, Poulose J, Malysz J, Zhu J, Fanburg-Smith JC, Claxton DF, Bayerl MG. 2019. Impact of ruxolitinib on myelofibrosis patients post allogeneic stem cell transplant-a pilot study. Br J Haematol. 186:e130-e133. doi:10.1111/bjh.15967.
Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.
Holokai L, Chakrabarti J, Broda T, Chang J, Hawkins JA, Sundaram N, Wroblewski LE, Peek RM, Wang J, Helmrath M, et al. 2019. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS Pathog. 15:e1007468. doi:10.1371/journal.ppat.1007468.
Instability in a coiled-coil signaling helix is conserved for signal transduction in soluble guanylyl cyclase.
Weichsel A, Kievenaar JA, Curry R, Croft JT, Montfort WR. 2019. Instability in a coiled-coil signaling helix is conserved for signal transduction in soluble guanylyl cyclase. Protein Sci. 28:1830–1839. doi:10.1002/pro.3707.
Integrated Meta-omics Reveals a Fungus-Associated Bacteriome and Distinct Functional Pathways in Clostridioides difficile Infection.
Stewart DB, Wright JR, Fowler M, McLimans CJ, Tokarev V, Amaniera I, Baker O, Wong H-T, Brabec J, Drucker R, et al. 2019. Integrated Meta-omics Reveals a Fungus-Associated Bacteriome and Distinct Functional Pathways in Clostridioides difficile Infection. mSphere. 4. doi:10.1128/mSphere.00454-19.
Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast.
Kunkel J, Luo X, Capaldi AP. 2019. Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast. Nat Commun. 10:3558. doi:10.1038/s41467-019-11540-y.
Integrative Epigenetic and Gene Expression Analysis of Renal Tumor Progression to Metastasis
Nam H-Y, Chandrashekar DS, Kundu A, Shelar S, Kho E-Y, Sonpavde G, Naik G, Ghatalia P, Livi CB, Varambally S, et al. 2019. Integrative Epigenetic and Gene Expression Analysis of Renal Tumor Progression to Metastasis. Molecular Cancer Research. 17(1):84–96.
Integrin α6β4E variant is associated with actin and CD9 structures and modifies the biophysical properties of cell-cell and cell-extracellular matrix interactions.
Wang M, Hinton JP, Gard JMC, Garcia JGN, Knudsen BS, Nagle RB, Cress AE. 2019. Integrin α6β4E variant is associated with actin and CD9 structures and modifies the biophysical properties of cell-cell and cell-extracellular matrix interactions. Mol Biol Cell. 30:838–850. doi:10.1091/mbc.E18-10-0652.
Iron as a Central Player and Promising Target in Cancer Progression.
Jung M, Mertens C, Tomat E, Brüne B. 2019. Iron as a Central Player and Promising Target in Cancer Progression. Int J Mol Sci. 20. doi:10.3390/ijms20020273.
Is There a Role for Cancer-Directed Surgery in Early-Stage Sarcomatoid or Biphasic Mesothelioma?
Kim S, Bull DA, Garland L, Khalpey Z, Stea B, Yi S, Hsu CC. 2019. Is There a Role for Cancer-Directed Surgery in Early-Stage Sarcomatoid or Biphasic Mesothelioma?. Ann Thorac Surg. 107:194–201. doi:10.1016/j.athoracsur.2018.07.081.
Jayakumar, A., and A. L. M. Bothwell, "RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors.", Cancer Res, vol. 79, issue 7, pp. 1587-1599, 2019 04 01. PMCID: PMC7395226 PMID: 30786994
Jayakumar, A., and A. L. M. Bothwell, "RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors.", Cancer Res, vol. 79, issue 7, pp. 1587-1599, 2019 04 01. PMCID: PMC7395226 PMID: 30786994. 2019.
Long-Term Exposure to Ozone and Cause-Specific Mortality Risk in the United States.
Lim CC, Hayes RB, Ahn J, Shao Y, Silverman DT, Jones RR, Garcia C, Bell ML, Thurston GD. 2019. Long-Term Exposure to Ozone and Cause-Specific Mortality Risk in the United States. Am J Respir Crit Care Med. 200:1022–1031. doi:10.1164/rccm.201806-1161OC.
Long-Term Exposure to Ozone and Cause-Specific Mortality Risk in the United States.
Lim CC, Hayes RB, Ahn J, Shao Y, Silverman DT, Jones RR, Garcia C, Bell ML, Thurston GD. 2019. Long-Term Exposure to Ozone and Cause-Specific Mortality Risk in the United States. Am J Respir Crit Care Med. 200:1022–1031. doi:10.1164/rccm.201806-1161OC.
Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes.
Engevik AC, Kaji I, Postema MM, Faust JJ, Meyer AR, Williams JA, Fitz GN, Tyska MJ, Wilson JM, Goldenring JR. 2019. Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes. J Cell Biol. 218:3647–3662. doi:10.1083/jcb.201902063.
Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Bowen C, Ostrowski MC, Leone G, Gelmann EP. 2019. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Res. 79:4124–4134. doi:10.1158/0008-5472.CAN-18-4110.
Mapping urban air quality using mobile sampling with low-cost sensors and machine learning in Seoul, South Korea.
Lim CC, Kim H, Vilcassim MJR, Thurston GD, Gordon T, Chen L-C, Lee K, Heimbinder M, Kim S-Y. 2019. Mapping urban air quality using mobile sampling with low-cost sensors and machine learning in Seoul, South Korea. Environ Int. 131:105022. doi:10.1016/j.envint.2019.105022.