Xinxin Ding, PhD

xding@pharmacy.arizona.edu

Links

Department Profile

NCBI Bibliography

PhD, Biological Chemistry, Medical School, University of Michigan, 1988
BS, Biology (Medical Physiology), Nanjing University (Nanjing, China), 1982

Cancer Focus

Lung cancer
Chemical carcinogenesis
Cancer prevention
Mechanisms of chemical toxicity

Research Program Role

Cancer Biology Program

Display Name
Xinxin Ding, PhD

Publications

Domanico MC, Collette NM, Ubick E, Ding X, Buchholz BA, Van Winkle LS. 2025. DNA adducts form in mouse lung and liver after oral naphthalene exposure. Toxicological Sciences. 205(1):42–46. doi:10.1093/toxsci/kfaf017.

Evans VJ, Wu X, Tran KK, Tabofunda SK, Ding L, Yin L, Edwards P, Zhang Q-Y, Ding X, Van Winkle LS. 2024. Impact of aging and ergothioneine pre-treatment on naphthalene toxicity in lung. Toxicology Letters. 397:89–102. doi:10.1016/j.toxlet.2024.05.014.

Kelty J, Kovalchuk N, Uwimana E, Yin L, Ding X, Van Winkle L. 2022. In vitro airway models from mice, rhesus macaques, and humans maintain species differences in xenobiotic metabolism and cellular responses to naphthalene. American Journal of Physiology-Lung Cellular and Molecular Physiology. 323(3):L308–L328. doi:10.1152/ajplung.00349.2021.

Kovalchuk N, Jilek JL, Van Winkle LS, Cherrington NJ, Ding X. 2022. Role of Lung P450 Oxidoreductase in Paraquat-Induced Collagen Deposition in the Lung. Antioxidants. 11(2):219. doi:10.3390/antiox11020219.

He Y, Lian W, Ding L, Fan X, Ma J, Zhang Q-Y, Ding X, Lin G. 2020. Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites. Archives of Toxicology. 95(1):103–116. doi:10.1007/s00204-020-02921-0.