Tissue Acquisition and Cellular/Molecular Analysis

Personalized treatment of cancer is rapidly becoming a standard practice. There are a number of factors that contribute to the uniqueness of a patient that include the individual’s genome, the genome and epigenome of the cancer, disease presentation, gender, exposures, lifestyle, microbiome, and other comorbidities. The identification of specific biomarkers, signaling pathways, immune cell signatures and genetic mutations within tumors underlies molecular targeted therapies and new insights into cancer treatment. The Tissue Acquisition and Cellular/Molecular Analysis Shared Resource (TACMASR) is an essential resource that is integrated into the University of Arizona Cancer Center for the successful prevention, control and therapy of cancer.

The Tissue Acquisition and Cellular/Molecular Analysis Shared Resource (TACMASR) provides support and pathology-related services to UArizona Cancer Center and University of Arizona researchers on a fee-for-service basis. We strive to maximize research dollars through customized, cost-effective, and quality-controlled services.

This shared resource has a board-certified anatomic pathologist on staff with many years of clinical and experimental research experience.

TACMASR offers two primary types of services to UArizona Cancer Center and UArizona research investigators that include cellular and molecular analysi, and tissue acquisition and biobanking.

To build a project, get a quote, or order a service within iLab:
Step 1: Select “About Our Core” to learn more about this Shared Resource.
Step 2: Click here to login or sign up for an iLab account at the University of Arizona. For login help, email iLab-support@agilent.com.
Step 3: Once the login step is completed, obtaining prices, services and scheduling is available within the iLab system.

Please remember to acknowledge the Cancer Center Support Grant (P30 CA023074) when publishing manuscripts or abstracts that utilized the services of the University of Arizona Cancer Center’s Shared Resources and/or were derived from CCSG pilot funds. Suggested language: "Research reported in this [publication/press release] was supported by the National Cancer Institute of the National Institutes of Health under award number P30 CA023074.

The Tissue Acquisition and Cellular/Molecular Analysis Shared Resource (TACMASR) is a multi-faceted research service facility that offers:

  • Biorepository - procurement, storage, and retrieval of Cancer biorepository specimens as well as assistance with locating sample cohorts and access to other special collections. Contact Carole Kepler.
    • Acquisition and preservation of tissues and body fluids
    • Biospecimen banking and storage
  • Routine Histology - paraffin & frozen samples, routine & special stains, Tissue MicroArrays (TMA). Contact Jocelyn Fimbres.
  • Immunostaining and in situ hybridization - Immunohistochemistry (IHC), In Situ Hybridization (ISH) using validated antibody staining protocols on automated platforms. Contact Jocelyn Fimbres.
  • Pathology - experimental advice, quality control, and scoring.
    • Clinical and pathological annotation of surgical biospecimens
  • Digital Pathology, Imaging & Microscopy - brightfield slide scanning, brightfield and widefield fluorescence microscopic image capture, Leica SP5 confocal microscope (with live cell imaging capabilities), Nikon spinning disk confocal microscope, Nikon BioPipeline Slide Scanner, Nikon image analysis workstation, as well as assistance in accessing and using other microscopy techniques on campus. Contact Doug Cromey.
  • Organoid Generation and Culture.  Contact Yana Zavros

These services are provided on a fee-for-service basis to members of the University of Arizona Cancer Center and to University of Arizona research investigators.

University of Arizona Cancer Center, Levy Building
Lab - Room 0917
Office – Room 0914
1515 N. Campbell, Tucson, AZ 85724

UACC-TACMASS@uacc.arizona.edu

Lab
Phone: 520-626-7319
E-mail: TACMASR

General Questions: Betsy Dennison
Phone: 520-626-0326
E-mail: Betsyd@email.arizona.edu

 

Shared Resource Director, Tissue Acquisition Cellular and Molecular Analysis