Timothy W Secomb, PhD

Clinical and Translational Oncology Program


Trained as an applied mathematician, Dr. Secomb has been conducting research for more than 35 years focusing on the microcirculation, the network of extremely small blood vessels that supplies oxygen and nutrients to all parts of our tissues, including tumors. He uses mathematical and computational approaches to study blood flow and mass transport in the microcirculation, structural adaptation of vessels and angiogenesis and local regulation of blood flow in both the systemic and pulmonary circulations. Other areas of research include models for the pharmacodynamics of cancer drugs, and the mechanics of the left ventricle. He has published more than 180 peer-reviewed journal articles, obtaining more than 9,300 citations.

Cancer Focus

Theoretical modeling of tumor mass transport, pharmacodynamics, vascular adaptation and angiogenesis.