Teodora Georgieva, PhD

Shared Resource Co-Director, Experimental Mouse

Director, GEM Core

Molecular biology has always been my passion and area of expertise. Since I started working at the Genetically Engineered Models (GEM) Core in 2007, I have had the opportunity to enhance my skills in molecular genetics while contributing to a field that is crucial for medical research. I am well-qualified to provide state-of-the-art gene modeling for mice and cancer cell lines, catering to both current and potential core customers. I can offer designs for nearly any type of genetic modification using various genetic engineering techniques, including transgenesis and the cutting-edge CRISPR/Cas9 technology.

Cancer Focus

Since its inception in 2007, 20% of the GEM Production Unit's work has been dedicated to supporting members of the Cancer Center in collaboration with the EMSR’s Mouse Production Unit. We successfully provide these members with optimal design strategies for their research models and produce high-quality, efficiently generated gene-modified mice and cancer cell lines. Additionally, we offer guidance and troubleshooting assistance for genotyping and colony breeding challenges.

Display Name
Teodora Georgieva, PhD

Publications

Lee GJ, Hode V, Georgieva T, Rau J, Dodick DW, Schwedt TJ, Neugebauer V, Porreca F, Navratilova E. 2025. Prolactin-induced sensitization of trigeminal nociceptors promotes migraine co-morbidity in endometriosis. Cephalalgia. 45(1). doi:10.1177/03331024241313378.

Georgieva TG, Darmoul D, Chen H, Cui H, Rice PFS, Barton JK, Besselsen DG, Ignatenko NA. 2024. Kallikrein-Related Peptidase 6 Contributes to Murine Intestinal Tumorigenesis Driven by a Mutant Adenomatous polyposis coli Gene. Cancers. 16(22):3842. doi:10.3390/cancers16223842.

Bradshaw CM, Georgieva T, Tankersley TN, Taylor-Doyle T, Johnson L, Uhrlaub JL, Besselsen D, Nikolich J Ž. 2024. Cutting Edge: Characterization of Low Copy Number Human Angiotensin-Converting Enzyme 2–Transgenic Mice as an Improved Model of SARS-CoV-2 Infection. The Journal of Immunology. 212(4):523–528. doi:10.4049/jimmunol.2300591.

Kwak E-A, Pan CC, Ramonett A, Kumar S, Cruz-Flores P, Ahmed T, Ortiz HR, Lochhead JJ, Ellis NA, Mouneimne G, et al. 2022. βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling. Nature Communications. 13(1). doi:10.1038/s41467-022-28933-1.

Powell DA, Hsu AP, Shubitz LF, Butkiewicz CD, Moale H, Trinh HT, Doetschman T, Georgieva TG, Reinartz DM, Wilson JE, et al. 2022. Mouse Model of a Human STAT4 Point Mutation That Predisposes to Disseminated Coccidiomycosis. ImmunoHorizons. 6(2):130–143. doi:10.4049/immunohorizons.2200007.

Teodora Georgieva, PhD

Cancer Focus

Display NameTeodora Georgieva, PhD

Publications

Display Name
Teodora Georgieva, PhD