Rui Xiong, PhD


The Xiong lab is interested in translational research in two directions: 1) Identification of small molecules that can sensitize cold tumors to immune checkpoint inhibitors. The particular pathway we are interested in involves inducing mismatch repair deficiency to activate neoantigen presentation; 2) Developing new chemical technology to address some undruggable oncogenic targets, such as the KRAS G12D mutation.

Cancer Focus

Colon cancer, Pancreatic cancer, Breast cancer

Research Program Role
Clinical and Translational Oncology Program

Display Name
Rui Xiong, PhD