Robert Clark Lantz, PhD
Biography
Dr. Lantz is Professor Emeritus of Cellular and Molecular Medicine, and Professor, Division of Community, Environment and Policy at the University of Arizona. Dr. Lantz received his undergraduate degree in Physics from Juniata College (1970) and his doctorate in Physiology and Biophysics from West Virginia University (1975). After postdoctoral training at Rockefeller University and at Emory University, Dr. Lantz took a faculty position at West Virginia University. In 1987, he moved to the University of Arizona and has held the rank of Professor since 2001.
Cancer Focus
Over the past 35 years, Dr. Lantz has concentrated his research in the area of pulmonary toxicology. Research has focused on the effects of exposure to metals (arsenic and uranium) on lung structure and function. More recently. Research has focused on the effects of in utero and early postnatal exposure on adult disease. Data obtained from in vitro cell culture and in vivo animal models has been subsequently translated into human population studies to validate responses and identify potential adverse health outcomes.
Selected Publications
Witten, M. L., B. Chau, E. Sáez, S. Boitano, and C. R Lantz, "Early life inhalation exposure to mine tailings dust affects lung development.", Toxicol Appl Pharmacol, vol. 365, pp. 124-132, 2019 Feb 15. PMCID: PMC6349506 PMID: 30641074
Yellowhair, M., M. R. Romanotto, D. M. Stearns, and C. R Lantz, "Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells.", Toxicol Appl Pharmacol, vol. 349, pp. 29-38, 2018 06 15. PMCID: PMC5972677 PMID: 29698738
Smeester, L., P. A. Bommarito, E. M. Martin, R. Recio-Vega, T. Gonzalez-Cortes, E. Olivas-Calderon, C. R Lantz, and R. C. Fry, "Chronic early childhood exposure to arsenic is associated with a TNF-mediated proteomic signaling response.", Environ Toxicol Pharmacol, vol. 52, pp. 183-187, 2017 Jun. PMCID: PMC5796657 PMID: 28433805
Michel-Ramirez, G., R. Recio-Vega, G. Ocampo-Gomez, E. Palacios-Sanchez, M. Delgado-Macias, M. Delgado-Gaona, R. Clark Lantz, J. Gandolfi, and T. Gonzalez-Cortes, "Association between YAP expression in neoplastic and non-neoplastic breast tissue with arsenic urinary levels.", J Appl Toxicol, vol. 37, issue 10, pp. 1195-1202, 2017 Oct. PMCID: PMC5790116 PMID: 28524356
Gonzalez-Cortes, T., R. Recio-Vega, R. Clark Lantz, and B. T. Chau, "DNA methylation of extracellular matrix remodeling genes in children exposed to arsenic.", Toxicol Appl Pharmacol, vol. 329, pp. 140-147, 2017 08 15. PMCID: PMC5806512 PMID: 28579250