Jean M Wilson, PhD
Cancer Biology Program
Biography
BS in Biology from UC Riverside
Ph.D. in Anatomy from UC Davis
Postdoctoral study at Harvard University and the University of Lausanne
Appointed as an Assistant Professor at The University of Arizona in 1990
Cancer Focus
Aberrant Wnt signaling is a major cause of colon cancer. My laboratory studies how membrane trafficking affects this signaling pathway within the intestine using mouse models and in vitro enteroid cultures.
Selected Publications
Jamwal, D. R., D. Laubitz, C. A. Harrison, V. Figliuolo da Paz, C. M. Cox, R. Wong, M. Midura-Kiela, M. A. Gurney, D. G. Besselsen, P. Setty, et al., "Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice.", Gastroenterology, vol. 159, issue 4, pp. 1342-1356.e6, 2020 Oct. PMID: 32589883
Blum, I. R., C. Behling-Hess, M. Padilla-Rodriguez, S. Momtaz, C. Cox, and J. M. Wilson, "Rab22a regulates the establishment of epithelial polarity.", Small GTPases, pp. 1-12, 2020 Apr 17. PMID: 32281471
da Paz, V. Figliuolo, D. R. Jamwal, M. Gurney, M. Midura-Kiela, C. A. Harrison, C. Cox, J. M. Wilson, F. K. Ghishan, and P. R. Kiela, "Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells.", Front Immunol, vol. 10, pp. 304, 2019. PMCID: PMC6400992 PMID: 30873168
Engevik, A. C., I. Kaji, M. M. Postema, J. J. Faust, A. R. Meyer, J. A. Williams, G. N. Fitz, M. J. Tyska, J. M. Wilson, and J. R. Goldenring, "Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes.", J Cell Biol, vol. 218, issue 11, pp. 3647-3662, 2019 11 04. PMCID: PMC6829668 PMID: 31562230
Parker, S. S., C. Cox, and J. M. Wilson, "Rabs set the stage for polarity.", Small GTPases, vol. 9, issue 1-2, pp. 116-129, 2018 03 04. PMCID: PMC5902228 PMID: 28125340