Hsiao-Hui (Sherry) Chow, PhD
Shared Resource Co-Director, Analytical Chemistry
Cancer Prevention and Control Program
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Research Professor, Medicine
Research Associate Professor, Pharmaceutical Sciences
Research Associate Professor, Pharmacy Practice-Science
Analytical Chemistry Shared Resource
Biography
Dr. Chow is a Research Professor of Medicine at the University of Arizona Cancer Center (UACC). She has led the UACC Analytical Chemistry Shared Resource since 2001 and co-led the UACC Cancer Prevention and Control (CPC) Program since 2015. She has a long track record of leading early phase cancer prevention clinical trials, development and implementation of biochemical and molecular biomarkers for evaluation of cancer risk and drug efficacy, and pharmacokinetic/pharmacodynamics study design and data analysis.
Cancer Focus
Dr. Chow conducts clinical and translational research studies to identify potential targets for cancer prevention and to evaluate chemoprevention strategies. She has led a number of clinical trials to evaluate the potentials of different dietary compounds, repurposed drugs, and modified dosing schedules of established drugs for breast cancer prevention. In addition, she has led a NCI-funded Chemoprevention Consortium to conduct clinical investigations of various pharmaceutical and nutraceutical agents and vaccines for prevention of lung, breast, cervix, prostate, skin, esophageal, and head and neck cancer.
Selected Publications
J. A. Martinez, Chalasani, P., Thomson, C. A., Roe, D., Altbach, M., Galons, J. - P., Stopeck, A., Thompson, P. A., Villa-Guillen, D. Evelyn, and Chow, H. - H. Sherry, “Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol.”, BMC Cancer, vol. 16, p. 500, 2016. PMCID: PMC4950218 PMID: 27430256
A. María López, Pruthi, S., Boughey, J. C., Perloff, M., Hsu, C. - H., Lang, J. E., Ley, M., Frank, D., Taverna, J. A., and Chow, H. - H. Sherry, “Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk.”, Cancer Prev Res (Phila), vol. 9, no. 2, pp. 142-8, 2016. PMCID: PMC4740217 PMID: 26667449
J. A. Miller, Pappan, K., Thompson, P. A., Want, E. J., Siskos, A. P., Keun, H. C., Wulff, J., Hu, C., Lang, J. E., and Chow, H. - H. Sherry, “Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention.”, Cancer Prev Res (Phila), vol. 8, no. 1, pp. 86-93, 2015. PMCID: PMC4289656 PMID: 25388013
H. - H. Sherry Chow, Garland, L. L., Heckman-Stoddard, B. M., Hsu, C. - H., Butler, V. D., Cordova, C. A., Chew, W. M., and Cornelison, T. L., “A pilot clinical study of resveratrol in postmenopausal women with high body mass index: effects on systemic sex steroid hormones.”, J Transl Med, vol. 12, p. 223, 2014. PMCID: PMC4243716 PMID: 25115686
J. A. Miller, Lang, J. E., Ley, M., Nagle, R., Hsu, C. - H., Thompson, P. A., Cordova, C., Waer, A., and Chow, H. - H. Sherry, “Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer.”, Cancer Prev Res (Phila), vol. 6, no. 6, pp. 577-84, 2013. PMCID: PMC3692564 PMID: 23554130