Frank Porreca, PhD

-
Professor, Pharmacology
Associate Department Head, Pharmacology
Biography
Frank Porreca is Professor of Pharmacology and Anesthesiology and a member of the University of Arizona Cancer Center. His laboratory studies mechanisms of chronic pain states including neuropathic, inflammatory, visceral, headache and cancer pain and mechanisms of opioid-induced hyperalgesia. He has trained many students and post-doctoral fellows and has published many peer-reviewed papers and other scientific writings. Among his awards and recognition, Professor Porreca was the recipient of the Ronald Melzack Award from the International Association for the Study of Pain, the F.W. Kerr Award from the American Pain Society and the P.D. Wall Award from the British Pain Society.
Cancer Focus
Cancer pain
Selected Publications
Navratilova, E., K. Nation, B. Remeniuk, V. Neugebauer, K. Bannister, A. H. Dickenson, and F. Porreca, "Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex.", Pain, vol. 161, issue 3, pp. 609-618, 2020 03. PMCID: PMC7124010 PMID: 31725062
Chen, Y., E. Navratilova, D. W. Dodick, and F. Porreca, "An Emerging Role for Prolactin in Female-Selective Pain.", Trends Neurosci, vol. 43, issue 8, pp. 635-648, 2020 08. PMID: 32620290
Remeniuk, B., T. King, D. Sukhtankar, A. Nippert, N. Li, F. Li, K. Cheng, K. C. Rice, and F. Porreca, "Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain.", Pain, vol. 159, issue 4, pp. 684-698, 2018 04. PMCID: PMC5911943 PMID: 29300279
Remeniuk, B., D. Sukhtankar, A. Okun, E. Navratilova, J. Y. Xie, T. King, and F. Porreca, "Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.", Pain, vol. 156, issue 10, pp. 1864-73, 2015 Oct. PMCID: PMC4578982 PMID: 25955964
Sukhtankar, D., A. Okun, A. Chandramouli, M. A. Nelson, T. W. Vanderah, A. E. Cress, F. Porreca, and T. King, "Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain.", Mol Pain, vol. 7, pp. 81, 2011 Oct 20. PMCID: PMC3212934 PMID: 22014040