Denise Roe, DrPH
Shared Resource Director, Biostatistics
Cancer Prevention and Control Program
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Professor, Public Health
Associate, Center for Toxicology
Director, Biometry Shared Services
Professor, Statistics-GIDP
Bioinformatics Shared ResourceBiostatistics Shared Resource
Biography
Denise J. Roe received a B.A. in Biology from the University of California, Los Angeles (UCLA), a M.S. in Biometrics from the University of Colorado, and a Dr.P.H. in Biostatistics from UCLA. She has been on the faculty of the University of Arizona since 1988. She was promoted to Professor in 2006 in the Department of Epidemiology and Biostatistics in the Mel and Enid Zuckerman College of Public Health. She has been the Director of the Biostatistics Shared Resource in the University of Arizona Cancer Center since 2009.
Cancer Focus
I have over 30 years of collaborative biostatistical experience working with University of Arizona Cancer Center (UACC) investigators in the design, conduct and statistical analysis of clinical, prevention and laboratory studies. I am the Biostatistics Shared Resource (BSR) Director, and facilitate the involvement of BSR faculty and staff in collaborative support for UACC investigators. I have served as the Biostatistics Core Director for multiple program project grants and SPORE applications, and as a co-investigator on multiple R01 and R21 grants. I also have collaborated with clinical investigators in the design, conduct, and statistical analysis of clinical trials, including three large (> 1000 patient) trials of adenomatous polyp prevention agents.
Selected Publications
G. Julian Augustus, Roe, D. J., Jacobs, E. T., Lance, P., and Ellis, N. A., “Is increased colorectal screening effective in preventing distant disease?”, PLoS One, vol. 13, no. 7, p. e0200462, 2018. PMCID: PMC6042755 PMID: 30001362
J. A. Martinez, Yang, J., Wertheim, B. C., Roe, D. J., Schriewer, A., Lance, P., Alberts, D. S., Hammock, B. D., and Thompson, P. A., “Celecoxib use and circulating oxylipins in a colon polyp prevention trial.”, PLoS One, vol. 13, no. 4, p. e0196398, 2018. PMCID: PMC5919576 PMID: 29698447
P. Łaniewski, Barnes, D., Goulder, A., Cui, H., Roe, D. J., Chase, D. M., and Herbst-Kralovetz, M. M., “Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women.”, Sci Rep, vol. 8, no. 1, p. 7593, 2018. PMCID: PMC5954126 PMID: 29765068
J. W. Bea, Funk, J., Hetherington-Rauth, M., Wertheim, B. C., Mosquiera, L., Thuraisingam, R., Lee, V., Blew, R., Lohman, T., Roe, D. J., and Going, S., “Anthropometry Versus Imaging for Prediction of Inflammation Among Hispanic Girls.”, Obesity (Silver Spring), vol. 26, no. 10, pp. 1594-1602, 2018. PMCID: PMC6171347 PMID: 30277029
P. Lance, Alberts, D. S., Thompson, P. A., Fales, L., Wang, F., San Jose, J., Jacobs, E. T., Goodman, P. J., Darke, A. K., Yee, M., Minasian, L., Thompson, I. M., and Roe, D. J., “Colorectal Adenomas in Participants of the SELECT Randomized Trial of Selenium and Vitamin E for Prostate Cancer Prevention.”, Cancer Prev Res (Phila), vol. 10, no. 1, pp. 45-54, 2017. PMCID: PMC5510661 PMID: 27777235
C. A. Thomson, Chow, H. H. Sherry, Wertheim, B. C., Roe, D. J., Stopeck, A., Maskarinec, G., Altbach, M., Chalasani, P., Huang, C., Strom, M. B., Galons, J. - P., and Thompson, P. A., “A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.”, Breast Cancer Res Treat, vol. 165, no. 1, pp. 97-107, 2017. PMCID: PMC5571834 PMID: 28560655
P. Lance, Thompson, P. A., Ashbeck, E. L., Roe, D. J., Fales, L., Buckmeier, J., Wang, F., Bhattacharyya, A., Hsu, C. - H., Chow, H. H. Sherry, Ahnen, D. J., C Boland, R., Heigh, R. I., Fay, D. E., Hamilton, S. R., Jacobs, E. T., Martinez, M. Elena, and Alberts, D. S., “Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes.”, J Natl Cancer Inst, vol. 108, no. 12, 2016. PMCID: PMC6272807 PMID: 27530657
J. A. Martinez, Chalasani, P., Thomson, C. A., Roe, D., Altbach, M., Galons, J. - P., Stopeck, A., Thompson, P. A., Villa-Guillen, D. Evelyn, and Chow, H. - H. Sherry, “Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol.”, BMC Cancer, vol. 16, p. 500, 2016. PMCID: PMC4950218 PMID: 27430256
T. H. Tate, Baggett, B., Rice, P. F. S., Koevary, J. Watson, Orsinger, G. V., Nymeyer, A. C., Welge, W. A., Saboda, K., Roe, D. J., Hatch, K. D., Chambers, S. K., Utzinger, U., and Barton, J. Kehlet, “Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection.”, J Biomed Opt, vol. 21, no. 5, p. 56005, 2016. PMCID: PMC5996865 PMID: 27220626
J. W. Bea, Thomson, C. A., Wertheim, B. C., J Nicholas, S., Ernst, K. C., Hu, C., Jackson, R. D., Cauley, J. A., Lewis, C. E., Caan, B., Roe, D. J., and Chen, Z., “Risk of Mortality According to Body Mass Index and Body Composition Among Postmenopausal Women.”, Am J Epidemiol, vol. 182, no. 7, pp. 585-96, 2015. PMCID: PMC4715226 PMID: 26350478