Denise Roe, DrPH

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Professor, Public Health
Associate, Center for Toxicology
Director, Biometry Shared Services
Professor, Statistics-GIDP
Bioinformatics Shared ResourceBiostatistics Shared Resource
Biography
Denise J. Roe received a B.A. in Biology from the University of California, Los Angeles (UCLA), a M.S. in Biometrics from the University of Colorado, and a Dr.P.H. in Biostatistics from UCLA. She has been on the faculty of the University of Arizona since 1988. She was promoted to Professor in 2006 in the Department of Epidemiology and Biostatistics in the Mel and Enid Zuckerman College of Public Health. She has been the Director of the Biostatistics Shared Resource in the University of Arizona Cancer Center since 2009.
Cancer Focus
I have over 30 years of collaborative biostatistical experience working with University of Arizona Cancer Center (UACC) investigators in the design, conduct and statistical analysis of clinical, prevention and laboratory studies. I am the Biostatistics Shared Resource (BSR) Director, and facilitate the involvement of BSR faculty and staff in collaborative support for UACC investigators. I have served as the Biostatistics Core Director for multiple program project grants and SPORE applications, and as a co-investigator on multiple R01 and R21 grants. I also have collaborated with clinical investigators in the design, conduct, and statistical analysis of clinical trials, including three large (> 1000 patient) trials of adenomatous polyp prevention agents.
Selected Publications
Łaniewski, P., D. Barnes, A. Goulder, H. Cui, D. J. Roe, D. M. Chase, and M. M. Herbst-Kralovetz, "Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women.", Sci Rep, vol. 8, issue 1, pp. 7593, 2018 May 15. PMCID: PMC5954126 PMID: 29765068
Bea, J. W., J. Funk, M. Hetherington-Rauth, B. C. Wertheim, L. Mosquiera, R. Thuraisingam, V. Lee, R. Blew, T. Lohman, D. J. Roe, et al., "Anthropometry Versus Imaging for Prediction of Inflammation Among Hispanic Girls.", Obesity (Silver Spring), vol. 26, issue 10, pp. 1594-1602, 2018 Oct. PMCID: PMC6171347 PMID: 30277029
Augustus, G. Julian, D. J. Roe, E. T. Jacobs, P. Lance, and N. A. Ellis, "Is increased colorectal screening effective in preventing distant disease?", PLoS One, vol. 13, issue 7, pp. e0200462, 2018. PMCID: PMC6042755 PMID: 30001362
Martinez, J. A., J. Yang, B. C. Wertheim, D. J. Roe, A. Schriewer, P. Lance, D. S. Alberts, B. D. Hammock, and P. A. Thompson, "Celecoxib use and circulating oxylipins in a colon polyp prevention trial.", PLoS One, vol. 13, issue 4, pp. e0196398, 2018. PMCID: PMC5919576 PMID: 29698447
Lance, P., D. S. Alberts, P. A. Thompson, L. Fales, F. Wang, J. San Jose, E. T. Jacobs, P. J. Goodman, A. K. Darke, M. Yee, et al., "Colorectal Adenomas in Participants of the SELECT Randomized Trial of Selenium and Vitamin E for Prostate Cancer Prevention.", Cancer Prev Res (Phila), vol. 10, issue 1, pp. 45-54, 2017 Jan. PMCID: PMC5510661 PMID: 27777235
Thomson, C. A., H. H. Sherry Chow, B. C. Wertheim, D. J. Roe, A. Stopeck, G. Maskarinec, M. Altbach, P. Chalasani, C. Huang, M. B. Strom, et al., "A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.", Breast Cancer Res Treat, vol. 165, issue 1, pp. 97-107, 2017 Aug. PMCID: PMC5571834 PMID: 28560655
Tate, T. H., B. Baggett, P. F. S. Rice, J. Watson Koevary, G. V. Orsinger, A. C. Nymeyer, W. A. Welge, K. Saboda, D. J. Roe, K. D. Hatch, et al., "Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection.", J Biomed Opt, vol. 21, issue 5, pp. 56005, 2016 05 01. PMCID: PMC5996865 PMID: 27220626
Lance, P., P. A. Thompson, E. L. Ashbeck, D. J. Roe, L. Fales, J. Buckmeier, F. Wang, A. Bhattacharyya, C-H. Hsu, H. H. Sherry Chow, et al., "Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes.", J Natl Cancer Inst, vol. 108, issue 12, 2016 12. PMCID: PMC6272807 PMID: 27530657
Martinez, J. A., P. Chalasani, C. A. Thomson, D. Roe, M. Altbach, J-P. Galons, A. Stopeck, P. A. Thompson, D. Evelyn Villa-Guillen, and H-H. Sherry Chow, "Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol.", BMC Cancer, vol. 16, pp. 500, 2016 07 19. PMCID: PMC4950218 PMID: 27430256
Bea, J. W., C. A. Thomson, B. C. Wertheim, S. J Nicholas, K. C. Ernst, C. Hu, R. D. Jackson, J. A. Cauley, C. E. Lewis, B. Caan, et al., "Risk of Mortality According to Body Mass Index and Body Composition Among Postmenopausal Women.", Am J Epidemiol, vol. 182, issue 7, pp. 585-96, 2015 Oct 01. PMCID: PMC4715226 PMID: 26350478