Jean M Wilson, PhD

Links

BS in Biology from UC Riverside
Ph.D. in Anatomy from UC Davis
Postdoctoral study at Harvard University and the University of Lausanne
Appointed as an Assistant Professor at The University of Arizona in 1990

Cancer Focus

Aberrant Wnt signaling is a major cause of colon cancer. My laboratory studies how membrane trafficking affects this signaling pathway within the intestine using mouse models and in vitro enteroid cultures.

Research Program Role

Cancer Biology Program

Display Name

Jean M Wilson, PhD

Publications

Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice.

Jamwal DR, Laubitz D, Harrison CA, Figliuolo da Paz V, Cox CM, Wong R, Midura-Kiela M, Gurney MA, Besselsen DG, Setty P, et al. 2020. Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice. Gastroenterology. 159:1342–1356.e6. doi:10.1053/j.gastro.2020.06.049.

Rab22a regulates the establishment of epithelial polarity.

Blum IR, Behling-Hess C, Padilla-Rodriguez M, Momtaz S, Cox C, Wilson JM. 2020 Apr. Rab22a regulates the establishment of epithelial polarity. Small GTPases.:1–12. doi:10.1080/21541248.2020.1754104.

Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes.

Engevik AC, Kaji I, Postema MM, Faust JJ, Meyer AR, Williams JA, Fitz GN, Tyska MJ, Wilson JM, Goldenring JR. 2019. Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes. J Cell Biol. 218:3647–3662. doi:10.1083/jcb.201902063.

Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells.

Figliuolo da Paz V, Jamwal DR, Gurney M, Midura-Kiela M, Harrison CA, Cox C, Wilson JM, Ghishan FK, Kiela PR. 2019. Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells. Front Immunol. 10:304. doi:10.3389/fimmu.2019.00304.

Rabs set the stage for polarity.

Parker SS, Cox C, Wilson JM. 2018. Rabs set the stage for polarity. Small GTPases. 9:116–129. doi:10.1080/21541248.2016.1277840.

Jean M Wilson, PhD

Links

Cancer Focus

Display Name Jean M Wilson, PhD

Publications

Display Name

Jean M Wilson, PhD