Reference
Simpson RJ, Bigley AB, Agha N, Hanley PJ, Bollard CM. 2017. Mobilizing Immune Cells With Exercise for Cancer Immunotherapy. Exerc Sport Sci Rev. 45:163–172. doi:10.1249/JES.0000000000000114.
Abstract
Hematopoietic stem cell (HSC) transplantation and adoptive transfer immunotherapy are effective in treating blood cancers and posttransplant infections, but low-circulating cell numbers in patients and donors are oftentimes a limiting factor. We postulate that a single exercise bout will increase the yield of patient- and donor-derived HSCs and cytotoxic lymphocytes to improve this form of treatment for cancer patients.