Tissue Acquisition and Cellular/Molecular Analysis
Personalized treatment of cancer is rapidly becoming a standard practice.
There are a number of factors that contribute to the uniqueness of a patient that include the individual’s genome, the genome and epigenome of the cancer, disease presentation, gender, exposures, lifestyle, microbiome, and other comorbidities.
The identification of specific biomarkers, signaling pathways, immune cell signatures and genetic mutations within tumors underlies molecular targeted therapies and new insights into cancer treatment.
The Tissue Acquisition and Cellular/Molecular Analysis Shared Resource (TACMASR) is integrated into the University of Arizona Cancer Center and provides support for studies related to advancing our understanding of the pathogenesis of cancers for the successful prevention, control and therapy of disease.
The Tissue Acquisition and Cellular/Molecular Analysis Shared Resource provides support and pathology-related services to Cancer Center and U of A researchers on a fee-for-service basis.
We strive to support investigator research endeavors through customized, cost-effective, and quality-controlled services including tissue acquisition, digital pathology, imaging and microscopy, histology and immunohistochemistry, and organoid culture.
TACMASR Services
- Paraffin & frozen samples
- Routine & special stains
Immunohistochemistry (IHC), In Situ Hybridization (ISH) using validated antibody staining protocols on automated platforms
Contact: Jayati Chakrabarti for organoid services
TACMASR + Biospecimen Core + Flow Cytometry
Through close collaboration with the Biospecimen Services Core, TACMASR aids investigators by collecting, embedding and processing tissue or collecting fresh tissues for analysis through Flow Cytometry (FCIMSR) or organoid preparation.
TACMASR EQUIPMENT
- Leica ASP3005 Tissue Processor
- HistoCore Arcadia H/C
- Brady IP300 slide/cassette label printer.
- Leica CM1520 Cryostat
- Leica HistoCore Biocut Microtome
- Microm HM315 Microtome
- Leica AutoStainer XL
- Leica CV5030 Coverslipper
- Leica Bond RXm
These services are provided on a fee-for-service basis to members of the Cancer Center and to University of Arizona research investigators. Cancer Center members receive the benefit of priority in access and delivery of services.
Request ServicesDownload Service Request Form TACMASR SOPs
Location:
University of Arizona Cancer Center, Levy Building
Lab - Room 0917
Office – Room 0914
1515 N. Campbell, Tucson, AZ 85724